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Accession IconGSE89846

Master Regulators of oncogenic KRAS response in Pancreatic Cancer

Organism Icon Mus musculus
Sample Icon 24 Downloadable Samples
Technology Badge IconIllumina MouseWG-6 v2.0 R2 expression beadchip

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Description
We derived a transcriptional signature of oncogenic KRAS by using the KF508 murine pancreatic ductal cell line with an inducible Lox-Stop-Lox (LSL) cassette in front of the KRASG12D oncogene to regulate transcription. This dataset allowed us to study the differential expression profile after oncogenic KRAS induction in mouse.
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