Interferon protects primary macrophages against HIV infection

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GSE83716

Homo sapiens

6 Downloadable Samples

Affymetrix Human Gene 2.0 ST Array (hugene20st)

Submitter Supplied Information

Description

Interferon (IFN) is a unique type I IFN that is not induced by pattern-recognition response elements. IFN is constitutively expressed in mucosal tissues including the female genital mucosa. We show here that IFN induces an antiviral state in human macrophages that blocks HIV-1 replication.

PubMed ID

27942584

Publication Title

IFN-<b>ε</b> protects primary macrophages against HIV infection.

Total Samples

Submitter’s Institution

PHRI, NJMS, Rutgers the State University of NJ

Authors

Tasker C, Subbian S, Gao P, Couret J, Levine C, Ghanny S, Soteropoulos P, Zhao X, Landau N, Lu W, Chang TL

Source Repository

Gene Expression Omnibus (GEO)

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