Transcriptome Profile of the Vascular Endothelial Cell Response to Candida albicans

GSE8166

Homo sapiens

20 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2), Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description

We perform microarray analysis of HUVECs upon stimulation with virulent wildtype C. albicans strain SC5314 or its efg1/efg1 cph1/cph1 hyphal-deficient derivative strain CAN34 to compare the gene expression profiles elicited from HUVECs in response to these strains. In addition, these responses are compared to that of TNF-alpha induced responses to determine which responses are Candida-specific.

PubMed ID

18500935

Publication Title

Transcriptome profile of the vascular endothelial cell response to Candida albicans.

Total Samples

Submitter’s Institution

University of Tennessee Health Science Center

Authors

Barker KS, Park H, Phan QT, Xu L, Homayouni R, Rogers PD, Filler SG

Source Repository

Gene Expression Omnibus (GEO)

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