Neutrophils from ARDS patients and healthy volunteers, and healthy volunteer samples treated with PI3K inhibitors

GSE76293

Homo sapiens

92 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Rationale: The acute respiratory distress syndrome is refractory to pharmacological intervention. Inappropriate activation of alveolar neutrophils is believed to underpin this diseases complex pathophysiology, yet these cells have been little studied.

PubMed ID

27064380

Publication Title

Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition.

Total Samples

Submitter’s Institution

GSK

Authors

Juss JK, House D, Amour A, Begg M, Herre J, Storisteanu DM, Hoenderdos K, Bradley G, Lennon M, Summers C, Hessel EM, Condliffe A, Chilvers ER

Source Repository

Gene Expression Omnibus (GEO)

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