Expression data from non-small cell lung cancer cell line DV90 after Bromodomain and extra terminal domain (BET) inhibitor JQ1 treatment

GSE75960

Homo sapiens

23 Downloadable Samples

Affymetrix Human Gene 2.1 ST Array (hugene21st)

Submitter Supplied Information

Description

Bromodomain and extra terminal domain (BET) inhibition reduces occupancy of BET-family proteins at promoter and enhancer sites resulting in changes in the transcription of specific genes.

PubMed ID

27607580

Publication Title

Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents.

Total Samples

Submitter’s Institution

Bayer Pharma AG

Authors

Klingbeil O, Lesche R, Gelato KA, Haendler B, Lejeune P

Source Repository

Gene Expression Omnibus (GEO)

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