Analysis of TCERG1 depletion by exon arrays

GSE73815

Homo sapiens

8 Downloadable Samples

Affymetrix Human Human Exon 1.0 ST Array (huex10st)

Submitter Supplied Information

Description

TCERG1 is a highly conserved human protein implicated in interactions with the transcriptional and splicing machinery. To investigate TCERG1 function, we survey genome-wide changes in transcript and exon levels upon TCERG1 knockdown in HEK293T cells. Our data revealed that TCERG1 regulates different types of alternative spliced events, indicating a broad role in the regulation of alternative splicing.

PubMed ID

27844289

Publication Title

Transcriptional Elongation Regulator 1 Affects Transcription and Splicing of Genes Associated with Cellular Morphology and Cytoskeleton Dynamics and Is Required for Neurite Outgrowth in Neuroblastoma Cells and Primary Neuronal Cultures.

Total Samples

Submitter’s Institution

Instituto Parasitologa y Biomedicina Lpez-Neyra

Authors

Muñoz-Cobo JP, Sánchez-Hernández N, Gutiérrez S, El Yousfi Y, Montes M, Gallego C, Hernández-Munain C, Suñé C

Source Repository

Gene Expression Omnibus (GEO)

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