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Accession IconGSE7313

Expression data from non-infected and Salmonella Typhimurium infected mesenteric lymph nodes

Organism Icon Sus scrofa
Sample Icon 14 Downloadable Samples
Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

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Description
A first generation Affymetrix GeneChip Porcine genome array was used to profile the gene expression in porcine mesenteric lymph nodes over a time course of infection with S. Typhimurium, including the acute (8 hours post inoculation (hpi), 24 hpi, 48 hpi) and chronic (21 days post-inoculation (dpi)) stages of infection. Our objectives were to 1) identify and examine the stereotypical gene expression response within host MLN to S. Typhimurium infection, 2) characterize global host responses by revealing the specific features of the hosts innate immunity pathways, and 3) explore if and how S. Typhimurium may escape the host immune response and develop into a carrier state.
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15
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