Gene expression changes in a histone sprocket arginine mutant in histone H2A R78A

GSE68159

Saccharomyces cerevisiae

6 Downloadable Samples

Affymetrix Yeast Genome 2.0 Array (yeast2)

Submitter Supplied Information

Description

Examined gene expression changes in a histone H2A R78A mutant in Saccharomyces cerevisiae relative to wild-type cells. THe overall goal of this study was to determine the functions of histone 'sprocket' arginine residues, which insert into the DNA minor groove in the nucleosome. We examined the roles of sprocket arginine mutants in gene expression, histone incorporation, and DNA repair.

PubMed ID

25971662

Publication Title

Histone Sprocket Arginine Residues Are Important for Gene Expression, DNA Repair, and Cell Viability in Saccharomyces cerevisiae.

Total Samples

Submitter’s Institution

Washington State University

Authors

Hodges AJ, Gallegos IJ, Laughery MF, Meas R, Tran L, Wyrick JJ

Source Repository

Gene Expression Omnibus (GEO)

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