Max as a biological blockade that restricts meiotic process in ESCs

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GSE65700

Mus musculus

10 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

We explored Max ablation-mediated up-regulation of germ-related genes, especially meiosis-related genes in mouse embryonic stem cells which were cultured either under conventional mouse ES medium or 2i condition using inhibitors against MEK and GSK3b.

PubMed ID

27025988

Publication Title

Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells.

Total Samples

Submitter’s Institution

Saitama Medical University

Authors

Suzuki A, Hirasaki M, Hishida T, Wu J, Okamura D, Ueda A, Nishimoto M, Nakachi Y, Mizuno Y, Okazaki Y, Matsui Y, Izpisua Belmonte JC, Okuda A

Source Repository

Gene Expression Omnibus (GEO)

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