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Accession IconGSE64019

Mouse Smarcb1-deficient models recapitulate subtypes of human rhabdoid tumors.

Organism Icon Homo sapiens, Mus musculus
Sample Icon 80 Downloadable Samples
Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302), Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

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Description
Rhabdoid Tumors (RT) are highly aggressive tumors that are frequently localized in the central nervous system (CNS) where they are termed atypical teratoid and rhabdoid tumors (ATRT). We generated conditional Smarcb1-deficient mouse model leads to CNS Smarcb1-deficient tumors.
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