Comparison between gene expression in heart from Emd KO and control mice

The present research is devoted to the identification of gene(s) severely affected by EMD mutations, leading to striated muscle laminopathies and more specifically the cardiomyopathy. For this purpose, we developped a large-scale gene expression approach on heart and skeletal tissues from Emd KO mouse model.

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Muchir A, Pavlidis P, Bonne G, Hayashi YK, Worman HJ