Gene expression profile of HIF-1 silenced or non-silenced human DCs stimulated with A. fumigatus under normoxic or hypoxic conditions

DCs play a central role for the immune response against the mold Aspergillus fumigatus. Hypoxic microenvironments occur during infection with A. fumigatus. Hypoxia and signaling via hypoxia inducible factor 1 may modulate the response of DCs; however, the role in fungal infections is unclear.

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