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Accession IconGSE59562

Gene expression data of the Arabidopsis thaliana mutant aladin

Organism Icon Arabidopsis thaliana
Sample Icon 12 Downloadable Samples
Technology Badge Icon Arabidopsis Gene 1.0 ST Array (aragene10st)

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Description
The ALADIN protein is a component of the nuclear pore complex in higher eukaryotes. Alteration in ALADIN is the basis for the human disease called triple A syndrome (Achalasia-Addisonianism-Alacrima Syndrome). A recent report showed that ALADIN deficiency decreases the tolerance to oxidative stress in human cells and impairs their ability to proliferate. An ALADIN homologue exists in plants, but its functions are still unknown. Therefore, the role of ALADIN was investigated in Arabidopsis thaliana in link with the regulation of the cell cycle.
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