Gene expression profiles in heterogeneous stock rats that differ in glucose tolerance

Using heterogeneous stock (HS) rats, we have identified a region on rat chromosome 1 that maps multiple diabetic traits. We sought to use global expression analysis to determine if genes within this region are differentially expressed between HS rats with normal glucose tolerance and those with glucose intolerance

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Tsaih SW, Holl K, Jia S, Kaldunski M, Tschannen M, He H, Andrae JW, Li SH, Stoddard A, Wiederhold A, Parrington J, Ruas da Silva M, Galione A, Meigs J, Meta-Analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) Investigators., Hoffmann RG, Simpson P, Jacob H, Hessner M, Solberg Woods LC