Gene expression in primary human macrophages and foam cells

GSE54666

Homo sapiens

12 Downloadable Samples

Illumina HumanHT-12 V4.0 expression beadchip

Submitter Supplied Information

Description

The aim of the experiment was to determine the effects of 48 hours of treatment with oxidized low density lipoprotein (oxLDL) on gene expression in primary human monocyte-derived macrophages.

PubMed ID

25835000

Publication Title

Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding.

Total Samples

Submitter’s Institution

University of Oxford

Authors

Reschen ME, Gaulton KJ, Lin D, Soilleux EJ, Morris AJ, Smyth SS, O'Callaghan CA

Source Repository

Gene Expression Omnibus (GEO)

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