Gene expression profiling in psoriatic lesional and non-lesional skin [brodalumab treatment]

GSE53552

Homo sapiens

78 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

To explore the psoriasis phenotype and pathways involved in psoriasis, we characterized gene expression in lesional and non-lesional skin from psoriasis patients. Furthermore, we explored the effects of various doses of brodalumab on lesional skin over time.

PubMed ID

24646743

Publication Title

Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody.

Total Samples

Submitter’s Institution

BJ Group, LLC

Authors

Russell CB, Rand H, Bigler J, Kerkof K, Timour M, Bautista E, Krueger JG, Salinger DH, Welcher AA, Martin DA

Source Repository

Gene Expression Omnibus (GEO)

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