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Accession IconGSE53494

Growth inhibition by Merlin expression correlates with a cross-tissue transcriptional signature

Organism Icon Homo sapiens
Sample Icon 24 Downloadable Samples
Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

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Description
We have found a broad case of tumour suppressor hypersensitivity for Merlin in cancer: Merlin expression in Merlin deficient cells (but not Merlin wild type cells) strongly suppresses proliferation regardless of tumour type or of additional somatic mutations.
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