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Accession IconGSE53174

Genome-wide analysis of whole-lung and alveolar macrophages before and after gut microbiome depletion

Organism Icon Mus musculus
Sample Icon 32 Downloadable Samples
Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

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Pneumonia accounts for more deaths than any other infectious disease worldwide. The intestinal microbiota has emerged as a key defense system by local support of mucosal immunity as well as proposed modulatory effects on systemic immunity. We here investigated the transcriptomes of whole-lungs and alveolar macrophages between untreated and antibiotic treated mice.
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