github link
Accession IconGSE53031

Gene expression profiling of human breast cancer during pregnancy

Organism Icon Homo sapiens
Sample Icon 167 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U219 Array (hgu219)

Submitter Supplied Information

Description
Using a dataset of 54 pregnant and 113 age/stage-matched non-pregnant breast cancer patients with complete clinical and survival data; we evaluated the pattern of hot spot somatic mutations and performed transcriptomic profiling using Sequenom and Affymetrix, respectively. Breast cancer molecular subtypes were defined using PAM50 and 3-Gene classifiers. We performed Gene set enrichment analysis (GSEA) to evaluate pathways associated with diagnosis during pregnancy. We investigated the differential expression of cancer-related genes and published gene sets according to pregnancy. We finally investigated genes associated with disease-free survival.
PubMed ID
Total Samples
167
Submitter’s Institution

Samples

Show of 0 Total Samples
Filter
Add/Remove
Accession Code
Title
Age
Disease stage
Processing Information
Additional Metadata
No rows found
Loading...