Whole transcriptome analysis of erlotinib treatment in EGFR-mutant cells

GSE51212

Homo sapiens

14 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

We were interested in characterizing the transcriptional changes that occur on a genome-wide scale following treatment of EGFR-mutant lung cancer cells with targeted therapies.

PubMed ID

25686219

Publication Title

Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways.

Total Samples

Submitter’s Institution

Massachusetts General Hospital

Authors

Rothenberg SM, Concannon K, Cullen S, Boulay G, Turke AB, Faber AC, Lockerman EL, Rivera MN, Engelman JA, Maheswaran S, Haber DA

Source Repository

Gene Expression Omnibus (GEO)

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