Genomic responses to Phenobarbital in Drosophila melanogaster

Phenobarbital is a well studied xenobiotic compound. In this study, we describe the genomic responses in fruit flies and examine whether animals mutant for DHR96, an ortholog of xenobiotic nuclear receptors PXR and CAR, plays a role in mediating xenobiotic responses in Drosophila.

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King-Jones K, Horner MA, Lam G, Thummel CS