Expression data from human pancreatic cells PANC-1 infected with oncolytic vaccinia virus GLV-1h153

GSE48121

Homo sapiens

8 Downloadable Samples

Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Submitter Supplied Information

Description

Pancreatic cancer is a fatal disease associated with resistance to conventional therapies. GLV-1h153 is an oncolytic virus which has shown promise for the targeted treatment of cancer, and is engineered to carry the human sodium iodide symporter (hNIS) for the imaging of viral replication within tumors via enhanced uptake of several radionuclide probes.

PubMed ID

27119120

Publication Title

Molecular network, pathway, and functional analysis of time-dependent gene changes associated with pancreatic cancer susceptibility to oncolytic vaccinia virotherapy.

Total Samples

Submitter’s Institution

Memorial Sloan-Kettering Cancer Center

Authors

Haddad D, Socci N, Chen CH, Chen NG, Zhang Q, Carpenter SG, Mittra A, Szalay AA, Fong Y

Source Repository

Gene Expression Omnibus (GEO)

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