github link
Accession IconGSE469

Temporal profiling in muscle regeneration.

Organism Icon Mus musculus
Sample Icon 66 Downloadable Samples
Technology Badge Icon Affymetrix Murine Genome U74A Array (mgu74a)

Submitter Supplied Information

Description
Temporal expression profiling was utilized to define transcriptional regulatory pathways in vivo in a mouse muscle regeneration model. Potential downstream targets of MyoD were identified by temporal expression, promoter data base mining, and gel shift assays; Slug and calpain 6 were identified as novel MyoD targets. Slug, a member of the snail/slug family of zinc finger transcriptional repressors critical for mesoderm/ectoderm development, was further shown to be a downstream target by using promoter/reporter constructs and demonstration of defective muscle regeneration in Slug null mice.
PubMed ID
Total Samples
66
Submitter’s Institution

Samples

Show of 0 Total Samples
Filter
Add/Remove
Accession Code
Title
Processing Information
Additional Metadata
No rows found
Loading...