Transcriptome Profile of G12-depleted OSCC cells

The elevation of guanine nucleotide binding protein alpha 12 (G12) expression is highly associated with tumor invasiveness in several human cancers. We used an siRNA strategy to deplete G12 in oral squamous cell carcinoma (OSCC) cells and analyze the transcriptome profile by the Affymetrix Human Exon 1.0 ST platform.

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Jian SL, Hsieh HY, Liao CT, Yen TC, Nien SW, Cheng AJ, Juang JL