Exon-level expression profiling of normal colonic mucosa samples.

These samples have been analyzed for global alternative splicing variation on exon-level expression data using the FIRMA algorithm. We have identified and described transcriptome instability as a genome-wide, pre-mRNA splicing related characteristic of solid cancers.

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Sveen A, Johannessen B, Teixeira MR, Lothe RA, Skotheim RI