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Accession IconGSE40442

Gene expression profiling in primary AML cells treated with decitabine and cytarabine

Organism Icon Homo sapiens
Sample Icon 66 Downloadable Samples
Technology Badge Icon Affymetrix Human Human Exon 1.0 ST Array (huex10st), Affymetrix Human Exon 1.0 ST Array [probe set (exon) version (huex10st)

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Description
Acute myeloid leukemia (AML), and other myeloid malignancies, are frequently treated with hypomethylating agents like decitabine. Alterations in the epigenome, induced by decitabine, are likely to result in gene expression changes. The effects of decitabine have not been systemically studied using primary AML samples.
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