Testis Gene Expression Changes after JQ1 treatment

GSE37894

Mus musculus

6 Downloadable Samples

Illumina MouseWG-6 v2.0 expression beadchip

Submitter Supplied Information

Description

JQ1 is a small-molecule (BET family) bromodomain inhibitor that causes a contraceptive effect in mice by blocking spermatogenesis and reducing sperm motility.

PubMed ID

22901802

Publication Title

Small-molecule inhibition of BRDT for male contraception.

Total Samples

Submitter’s Institution

Texas A&M University

Authors

Matzuk MM, McKeown MR, Filippakopoulos P, Li Q, Ma L, Agno JE, Lemieux ME, Picaud S, Yu RN, Qi J, Knapp S, Bradner JE

Source Repository

Gene Expression Omnibus (GEO)

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