Re-activation of EWS-FLI1 suppressed FOXO1 expression as a novel therapeutic strategy for Ewings sarcoma

GSE37409

Homo sapiens

11 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Transient transfection of a Ewing's Sarcoma cell line expressing type I EWS-FLI1 fusion and doxycycline-inducible short hairpin RNA against EWS-FLI1 (A673sh)

PubMed ID

23995784

Publication Title

Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma.

Total Samples

Submitter’s Institution

CCRI, St.Anna Children Cancer Research Institute

Authors

Niedan S, Kauer M, Aryee DN, Kofler R, Schwentner R, Meier A, Pötschger U, Kontny U, Kovar H

Source Repository

Gene Expression Omnibus (GEO)

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