Transcriptional profiling of clinically relevant SERMs and SERM/estradiol complexes in a cellular model of breast cancer

GSE35428

Homo sapiens

106 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

In this study, we have utilized microarray analysis to directly compare a subset of structurally distinct, clinically relevant SERMs in the presence and absence of estradiol, using a high replicate number (10) to ensure detection of modestly regulated genes.

PubMed ID

22570330

Publication Title

Research resource: Transcriptional profiling in a cellular model of breast cancer reveals functional and mechanistic differences between clinically relevant SERM and between SERM/estrogen complexes.

Total Samples

106

Submitter’s Institution

Emory University

Authors

Wardell SE, Kazmin D, McDonnell DP

Source Repository

Gene Expression Omnibus (GEO)

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