Meta-analysis of global transcriptomics of Quercetin and Tannic acid exposed C. elegans

GSE35354

Caenorhabditis elegans

24 Downloadable Samples

Affymetrix C. elegans Genome Array (celegans)

Submitter Supplied Information

Description

Recent research has highlighted that the polyphenols Quercetin (Q) and Tannic acid (TA) are capable of extending the lifespan of C. elegans. To gain a deep understanding of the underlying molecular genetics, we analyzed the global transcriptional patterns of nematodes exposed to Quercetin or Tannic acid concentrations that are non-effective (in lifespan extension), lifespan extending or toxic.

PubMed ID

22493606

Publication Title

Meta-Analysis of Global Transcriptomics Suggests that Conserved Genetic Pathways are Responsible for Quercetin and Tannic Acid Mediated Longevity in C. elegans.

Total Samples

Submitter’s Institution

King's College London

Authors

Pietsch K, Saul N, Swain SC, Menzel R, Steinberg CE, Stürzenbaum SR

Source Repository

Gene Expression Omnibus (GEO)

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