Microarray data Ptf1a gain-of-function Xenopus pancreas development

The Ptf1a gene has essential functions during several stages of pancreas development. It is expressed in the nave endoderm and required pancreas cell fate specification; it is also required later in the differentiation and maintenance of acinar cells. To identify the regulatory genetic program downstream of Ptf1a required for early pancreatic fate acquisition, we used microarrays to perform a comprehensive gene expression analysis of Ptf1a overexpressing endodermal tissue at NF32 and NF36.

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