Muscle Satellite Cells: MyoD and p53 genes

GSE3244

Mus musculus

25 Downloadable Samples

Affymetrix Murine Genome U74A Version 2 Array (mgu74av2), Affymetrix Murine Genome U74A Array (mgu74a)

Submitter Supplied Information

Description

Muscle satellite cells are a self-renewing pool of stem cells that give rise to daughter myogenic precursor cells in adult skeletal muscle. Published and preliminary data indicated that MyoD and p53 genes are involved in satellite cell differentiation. We would like to know what downstream genes of both transcription factors are affected in satellite cell-derived myoblasts (MyoD-/-, p53 -/-).

PubMed ID

16275751

Publication Title

MyoD induces myogenic differentiation through cooperation of its NH2- and COOH-terminal regions.

Total Samples

Submitter’s Institution

Ontario Genomics Innovation Centre (OGIC)

Authors

Ishibashi J, Perry RL, Asakura A, Rudnicki MA

Source Repository

Gene Expression Omnibus (GEO)

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