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Accession IconGSE32331

Early downstream targets of Notch signaling which contribute to multiciliate cell fate

Organism Icon Xenopus laevis
Sample Icon 4 Downloadable Samples
Technology Badge Icon Affymetrix Xenopus laevis Genome 2.0 Array (xlaevis2)

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Description
Analysis of epithelial explants injected with the intracellular domain of Notch (ICD) to block the formation of multi-ciliate and proton secreting cells or with dominant negative human Mastermind (HMM) or a DNA binding mutant of Mastermind (DBM) to induce the formation of ectopic multi-ciliate and proton secreting cells. Results show which genes are up or down-regulated when DBM/HMM are compared to ICD.
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