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Accession IconGSE28574

Transcriptome expressed in the mouse suprachiasmatic nucleus

Organism Icon Mus musculus
Sample Icon 1 Downloadable Sample
Technology Badge Icon Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

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Description
This array set was used to identify the genes that are highly expressed in the mouse suprachiasmatic nucleus (SCN). Because pharmacological inhibition of Gai/o activity with pertussis toxin hampers intercellular synchronization and causes dampened rhythms of the entire SCN, we hypothesized that member(s) of the Regulator of G protein Signaling (RGS) family might contribute to synchronized cellular oscillations in the SCN. To test this hypothesis, we surveyed all known mouse Rgs genes for their expression by using GeneChip and selected the genes that are highly expressed in the SCN for further analysis.
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