AMPK and calcineurin induced longevity is mediated by CRTC-1 and CREB

GSE25513

Caenorhabditis elegans

12 Downloadable Samples

Affymetrix C. elegans Genome Array (celegans)

Submitter Supplied Information

Description

AMPK (AAK-2) and calcineurin (TAX-6) mediate longevity exclusively through post-translational modification of CRTC-1, the sole C. elegans CRTC (CREB regulated transcriptional coactivator).

PubMed ID

21331044

Publication Title

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.

Total Samples

Submitter’s Institution

Salk Institute for Biological Studies

Authors

Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A

Source Repository

Gene Expression Omnibus (GEO)

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