Human Fetal and Adult Peripheral Nave CD4+ T cells and CD4+CD25+ Treg cells

GSE25087

Homo sapiens

11 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

We compared differences in fetal and adult T cells by performing whole genome profiling on sort-purified T cells (nave CD4+ and Treg cells) from human fetal specimens (18-22 gestational weeks) and adult specimens (age 25-40 years old). Fetal and Adult Nave CD4+ T cells phenotype: CD3+CD4+CD45RA+CCR7+CD27+, Fetal and Adult CD4+CD25+ Treg phenotype: CD3+CD4+CD25bright

PubMed ID

21164017

Publication Title

Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans.

Total Samples

Submitter’s Institution

University of California San Francisco

Authors

Mold JE, Venkatasubrahmanyam S, Burt TD, Michaëlsson J, Rivera JM, Galkina SA, Weinberg K, Stoddart CA, McCune JM

Source Repository

Gene Expression Omnibus (GEO)

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