github link
Accession IconGSE23768

Diverse somatic mutation patterns and pathway alterations in human cancers

Organism Icon Homo sapiens
Sample Icon 150 Downloadable Samples
Technology Badge Icon Affymetrix Human Exon 1.0 ST Array [probe set (exon) version (huex10st), Affymetrix Human Human Exon 1.0 ST Array (huex10st)

Submitter Supplied Information

Description
The systematic characterization of somatic mutations in cancer genomes is essential for understanding the disease and for developing targeted therapeutics. Here we report the identification of 2,576 somatic mutations across approximately 1,800 megabases of DNA representing 1,507 coding genes from 441 tumours comprising breast, lung, ovarian and prostate cancer types and subtypes. Additionally, 373 tumors were assayed for copy number alterations via Agilent 244A CGH arrays and 153 breast, lung, and colon samples were assayed for mRNA abundance with Affymetrix HuEx1 Exon Arrays.
PubMed ID
Total Samples
526
Submitter’s Institution

Samples

Show of 0 Total Samples
Filter
Add/Remove
Accession Code
Title
Specimen part
Processing Information
Additional Metadata
No rows found
Loading...