Growth Hormone (GH) Treatment of 3T3-F442A Adipocytes

GSE2120

Mus musculus

18 Downloadable Samples

Affymetrix Murine Genome U74A Version 2 Array (mgu74av2)

Submitter Supplied Information

Description

Expression profiling of 3T3-F442A adipocytes treated with growth hormone (GH, 500 nM) or vehicle (DMEM + 1% BSA) control for 30 min., 4 hr., or 48 hr in three independent experiments. Chronic GH treatment induces metabolic changes consistent with insulin resistance in 3T3-F442A adipocytes.

PubMed ID

16326703

Publication Title

Profiles of growth hormone (GH)-regulated genes reveal time-dependent responses and identify a mechanism for regulation of activating transcription factor 3 by GH.

Total Samples

Submitter’s Institution

University of Michigan

Authors

Huo JS, McEachin RC, Cui TX, Duggal NK, Hai T, States DJ, Schwartz J

Source Repository

Gene Expression Omnibus (GEO)

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