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Accession IconGSE20031

Generation of Autologous Pluripotent Stem Cells from Adult Testis Biopsy

Organism Icon Mus musculus
Sample Icon 14 Downloadable Samples
Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

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Description
In regenerative medicine, histocompatibility of pluripotent stem cells is required to solve the problem of immunorejection after therapeutic transplantation. In this study, we show that autologous germline stem cells (GSCs), often called spermatogonial stem cells, could be derived by testis biopsy from individual mice and that GSCs subsequently could be dedifferentiated into autologous germline-derived pluripotent stem (gPS) cells.
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