Expression data from Th2 cell of ECM1 KO mice vs WT mice

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GSE19707

Mus musculus

2 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

CD4+ helper T cells are critical for immunological response. Th2 cells, a subset of CD4+ helper T cells, are responsible for asthma and other immune diseases. We found a Th2 secreted protein, ExtraCellular Matrix protein 1 (ECM1), which is highly induced by classic IL-4 signaling pathway during helper T cells differentiation.

PubMed ID

21217760

Publication Title

ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1).

Total Samples

Submitter’s Institution

Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

Authors

Li Z, Zhang Y, Liu Z, Wu X, Zheng Y, Tao Z, Mao K, Wang J, Lin G, Tian L, Ji Y, Qin M, Sun S, Zhu X, Sun B

Source Repository

Gene Expression Omnibus (GEO)

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