Effects of dynamic compressive loading on MSC chondrogenesis

GSE18879

Bos taurus

6 Downloadable Samples

Affymetrix Bovine Genome Array (bovine)

Submitter Supplied Information

Description

Long-term dynamic compression enhanced the mechanical properties of MSC-seeded constructs only when loading was initiated after 21 days of chondrogenic differentiation. This study examined the molecular differences of chondrogenic MSCs compared to undifferentiated MSCs (TGF-beta vs no TGF-beta) and the effects of dynamic loading on MSC chondrogenesis (loading vs free-swelling).

PubMed ID

20186667

Publication Title

Long-term dynamic loading improves the mechanical properties of chondrogenic mesenchymal stem cell-laden hydrogel.

Total Samples

Submitter’s Institution

University of Pennsylvania

Authors

Huang AH, Farrell MJ, Kim M, Mauck RL

Source Repository

Gene Expression Omnibus (GEO)

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