Pancreatic cancer circulating tumor cells express a cell motility gene signature that predicts survival after surgery

Most cancer deaths are caused by metastases, which are the end-results of circulating tumor cells (CTC) that detach from the cancer primary and succeed to survive in distant organs. The aim of the present study was to develop a gene signature of CTC and to assess its prognostic relevance after surgery for pancreatic ductaladenocarcinoma (PDAC).

24

Sergeant G, van Eijsden R, Roskams T, Van Duppen V, Topal B