Effect of deuterium oxide on Arabidopsis gene expression

2H2O has a long history as a protein or amino acid labeling techinique, and such labeling systems have proven effective for many different types of studies. A disadvantage of a 2H2O labeling system is that plant growth is inhibited as the percentage of deuterium in the medium increases. However the molecular effects of 2H2O on plant growth has not previoulsly been investigated.

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Yang XY, Chen WP, Rendahl AK, Hegeman AD, Gray WM, Cohen JD