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Accession IconGSE17758

Microarray analysis of changes in gene expression within the amacrine cell layer of chicks following optical defocus

Organism Icon Gallus gallus
Sample Icon 9 Downloadable Samples
Technology Badge Icon Affymetrix Chicken Genome Array (chicken)

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Description
Ocular growth is regulated locally by signals produced in the retina that ultimately act on the growth of the scleral tissue. Consequently, a number of studies have investigated changes in retinal gene expression during manipulation of ocular growth in an attempt to elucidate the biochemical pathways underlying eye growth. However, due to the highly heterogenous nature of the retina, important changes in gene expression can be masked. Therefore, this study has investigated changes in gene expression specifically within the retinal amacrine cell layer, the most likely generator of growth signals, during manipulations of ocular growth.
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