Gene expression analysis of rat livers treated with pharmaceutical development compounds

GSE17388

Rattus norvegicus

44 Downloadable Samples

Affymetrix Rat Genome U34 Array (rgu34a)

Submitter Supplied Information

Description

We used microarrays to analyze gene expression changes in liver after treatment of rats with two compounds from drug development (R1, R2) to identify potential effects related to hepatotoxicity.

PubMed ID

21671310

Publication Title

Gene expression-based in vivo and in vitro prediction of liver toxicity allows compound selection at an early stage of drug development.

Total Samples

Submitter’s Institution

Roche

Authors

Roth A, Boess F, Landes C, Steiner G, Freichel C, Plancher JM, Raab S, de Vera Mudry C, Weiser T, Suter L

Source Repository

Gene Expression Omnibus (GEO)

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