Expression data of two human cancer cell lines cultivated in 2-dimensional (2D) vs. 3-dimensional (3D) cell culture

GSE17347

Homo sapiens

7 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

3D cultivation of cells lead to changes in morphology of the cells. This is likely to explain the higher radioresistance of cells growing in 3D compared to cells growing in 2D cell culture.

PubMed ID

22509286

Publication Title

Genome-wide gene expression analysis in cancer cells reveals 3D growth to affect ECM and processes associated with cell adhesion but not DNA repair.

Total Samples

Submitter’s Institution

University Medical Center Hamburg-Eppendorf

Authors

Zschenker O, Streichert T, Hehlgans S, Cordes N

Source Repository

Gene Expression Omnibus (GEO)

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