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Accession IconGSE16975

Hydrogen sulfide (H2S) modulates lifespan of C.elegans

Organism Icon Caenorhabditis elegans
Sample Icon 6 Downloadable Samples
Technology Badge Icon Affymetrix C. elegans Genome Array (celegans)

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Description
Hydrogen sulfide (H2S) is formed naturally from L-cysteine in a variety of mammalian and non-mammalian cells. To date, numerous biological effects have been ascribed to H2S including control of cardiovascular, immune and nervous function. Over or under production of H2S has been observed in several disease states including hypertension and inflammation. In addition, it has been stipulated that H2S may affect the ageing process. The model nematode Caenorhabditis elegans is ideally suited for assessing drug effects on lifespan since it is relatively short-lived, can be easily exposed to drugs and its genome is fully sequenced and widely annotated.
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