Determining direct targets of the bHLH MIST1

The transcription factor MIST1 is required for final maturation of secretory cells of diverse tissues, including gastric digestive-enzyme secreting zymogenic (chief) cells (ZCs). Here, we show that MIST1 directly activates RAB26, RAB3D and several other genes.

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Tian X, Jin RU, Bredemeyer AJ, Oates EJ, Błazewska KM, McKenna CE, Mills JC