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Accession IconGSE157797

Transcriptional characterization of hippocampi from novel preclinical model of drug-resistant epilepsy

Organism Icon Mus musculus
Sample Icon 30 Downloadable Samples
Technology Badge IconIllumina MouseRef-8 v2.0 expression beadchip

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Description
A novel model of drug-resistant epilepsy based on the selection of mice treated with phenytoin (PHT) in the 6 Hz seizure model was developed. It leads to the identification of subpopulations of drug-responder and non-responder mice. Transcriptional characterization of the hippocampi from these 2 sub-populations was performed and compared. No significant difference has been observed between the 2 sample groups.
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