Over expression of mRNA for multiple genes including insulin in the PLN of NOD is associated with Islet Autoimmunity

GSE15582

Mus musculus

9 Downloadable Samples

Affymetrix Murine Genome U74A Version 2 Array (mgu74av2)

Submitter Supplied Information

Description

The aim of this study is to identify genes implicated in the early steps of the autoimmune process, prior to inflammation in type 1 diabetes. Early Insulin AutoAntibodies (E-IAA) have been used as subphenotypic marker to select individual animals as type 1 diabetes prone and to compare gene expression patterns with insulin autoantibody negative NOD.

PubMed ID

19799787

Publication Title

Early over expression of messenger RNA for multiple genes, including insulin, in the Pancreatic Lymph Nodes of NOD mice is associated with Islet Autoimmunity.

Total Samples

Submitter’s Institution

Institut Pasteur

Authors

Regnault B, Osorio Y Fortea J, Miao D, Eisenbarth G, Melanitou E

Source Repository

Gene Expression Omnibus (GEO)

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